The premier non-surgical treatment for lung cancer

Unrivaled precision — where it matters most.

One of the biggest challenges in lung cancer treatment remains effectively treating the cancer, while minimizing impact on the many sensitive tissues and vital organs that surround the lungs. Precision is critical — and that’s what makes the CyberKnife System so unique. The CyberKnife System is the only robotic radiation delivery system that incorporates Synchrony® Respiratory Technology, enabling the system to automatically and continually track and synchronize treatment delivery to motion to keep the radiation precisely targeted on the tumor as it moves with your natural breathing. The CyberKnife System is a leading technology in SBRT, a specialized type of radiation therapy, used to routinely treat lung cancers and metastases. The system provides a proven, non-surgical option for treating early stage, inoperable non-small cell lung cancer, tumors in challenging anatomical locations such as central lung tumors surrounded by sensitive structures and lung tumors near the chest wall, and inoperable peripheral lung tumors. CyberKnife SBRT may also be an option for those patients seeking an alternative to surgery.

Key CyberKnife® treatment benefits

Ask a physician if CyberKnife treatment is right for you

You deserve the best possible treatment for your lung cancer. Find a physician in your area offering the CyberKnife System — and find out if CyberKnife treatment is right for you.

More than two decades of clinical proof

The CyberKnife System is the first and only radiotherapy device that brings true robotic precision and the ability to track, detect and adapt for tumor motion in real-time, to the treatment of lung cancer. But this advanced treatment technology is not new; the CyberKnife System has more than two decades of clinical evidence and has helped thousands of patients diagnosed with lung tumors and metastases. The CyberKnife System is used to treat a wide range of lung cancers, including even the most complicated cases.

Demonstrated clinical benefits in the treatment of lung cancer:


1 Brown et al. “Application of Robotic Stereotactic Radiotherapy to Peripheral Stage I Non-small Cell Lung Cancer with Curative Intent.” Clin Oncol (R Coll Radiol). 2009; 21: 623-631.

2 Nuyttens J.J. et al. “Outcome of four-dimensional stereotactic radiotherapy for centrally located long tumors.” Radiotherapy and Oncology. 2012; 102: 383-387.

3 Podder T. et al. “Chest wall and rib irradiation and toxicities of early-stage lung cancer patients treated with CyberKnife stereotactic body radiotherapy.” Future oncology. 2014; 10(15): 2311-2317.

4 Snider J.W. et al. “CyberKnife with tumor tracking: an effective treatment for high-risk surgical patients with single peripheral lung metastases” Front Oncol. 2012; 2: 63 –

5 Lischalk J.W. et al. “Long-term outcomes of stereotactic body radiation therapy (sbrt) with fiducial tracking for inoperable stage I non-small cell lung cancer (nsclc).” J Radiat Oncol. 2016; 5: 379-387 –

6 Chang S. et al. “Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two rancomised trials.” Lancet Oncol. 2015; 16(6) 630-637 –

An ideal, non-surgical option

While surgery is often considered the gold standard of treatment, its application is frequently limited by the patient’s health, and the stage and location of the tumor. Despite its name, CyberKnife treatment is not a surgical procedure. In fact, there is no cutting involved. This makes the CyberKnife System an excellent treatment option when more invasive techniques are deemed inappropriate or too risky. CyberKnife treatment is also an ideal option in cases where patients cannot undergo surgical procedures as a result of:

The CyberKnife® System tracks your breathing — and attacks your tumor — in real-time

When you breathe, your torso moves. This means that a lung tumor will continuously move throughout the course of treatment delivery. Unlike any other radiation therapy device, the CyberKnife System uses the world’s only real-time motion synchronization technology to continuously track that motion and adapt treatment delivery to maintain sub-millimeter precision. This helps to ensure the radiation dose is delivered to the target — maximizing treatment effectiveness while minimizing dose to surrounding tissues to help reduce the incidence of side effects. And unlike other radiotherapy options, the CyberKnife System does not require uncomfortable patient restraints or breath-hold techniques; you can relax and breathe normally, with full confidence in the CyberKnife’s synchronization capabilities.

Enables re-treatment after previous radiation

Because the precise targeting of the CyberKnife System significantly reduces irradiation of surrounding healthy tissues, CyberKnife may be a treatment option for a wider range of lung cancer patients:

CyberKnife® vs. traditional treatments

An effective, less disruptive treatment option

The unparalleled precision and motion synchronization capabilities of the CyberKnife System maximize radiation delivered to the target — while helping minimize dose to surrounding healthy tissues. The result is highly effective treatment that eliminates many of the inconveniences of other treatments — and significantly reduces the risk of the side effects that too often disrupt the lives of patients during and after treatment. In fact, the hypofractionated, high-dose radiosurgery delivered by the CyberKnife System has been shown to improve tumor control and patient survival when compared to conventional radiotherapy.


Treatment with the CyberKnife System is an outpatient procedure that does not requires incisions or general anesthesia. Most patients will not require hospitalization, or a long recovery period.


CyberKnife treatment eliminates the inconvenience and risk associated with seed implants.


CyberKnife treatment is typically completed in as little as 3 to 4 sessions over 1 to 2 weeks, compared to 20 to 30 sessions over 4 to 6 weeks with conventional radiation therapy.

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Please note: Accuray is the manufacturer of the CyberKnife®, TomoTherapy®, and Radixact® Systems. As the manufacturer, we are unable to provide specific medical advice, view medical records, or schedule appointments.
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Important Safety Statement: Most side effects of radiotherapy, including radiotherapy delivered with Accuray systems, are mild and temporary, often involving fatigue, nausea, and skin irritation. Side effects can be severe, however, leading to pain, alterations in normal body functions (for example, urinary or salivary function), deterioration of quality of life, permanent injury and even death. Side effects can occur during or shortly after radiation treatment or in the months and years following radiation. The nature and severity of side effects depend on many factors, including the size and location of the treated tumor, the treatment technique (for example, the radiation dose), the patient’s general medical condition, to name a few. For more details about the side effects of your radiation therapy, and if treatment with an Accuray product is right for you, ask your doctor.